The bounties were posted on the U.S. State Department Rewards for Justice website late Monday, the U.S. Embassy in Islamabad said Tuesday.
The State Department website describes Saeed as a former professor of Arabic and engineering who heads an organization "dedicated to installing Islamist rule over parts of India and Pakistan." It also noted that six of the people killed in the 2008 Mumbai attacks were American citizens.
Indian External Affairs Minister S.M. Krishna welcomed the U.S. announcement, saying it would signal to Lashkar-e-Taiba and its patrons that the international community remains united in fighting terrorism.
"The decision reflects the commitment of India and the United States to bring the perpetrators of the Mumbai terrorist attack to justice and continuing efforts to combat terrorism," he said.